Association of Frailty with Serum Vitamin D and Parathyroid Hormone Levels

Objective: Studies investigating the effect of vitamin D and parathyroid hormone (PTH) in frailty syndrome are limited.Therefore, we aimed to evaluate the relationship between frailty and serum vitamin D and PTH levels.Material and Methods: This is a cross-sectional study conducted on individuals aged >65 years.In this cross-sectional study, data were collected using sociodemographic data sheet, Fatigue, Resistance, Ambulation, Illnesses, & Loss of Weight (FRAIL) scale and Study of Osteoporotic Fracture (SOF) index via face-to-face interview.The study included data from 513 subjects.Chi-square test was used in analyses.A p value<0.05 was considered as statistically significant. Results:The mean age was 71.9±6.4 years in the study population.The prevalence of frailty elder was found as 46.8% by FRAIL scale and 51.3% by SOF index while pre-fail elder prevalence was found as 45.2% by FRAIL scale and 33.3% by SOF index. Conclusion:In our study it was found that frail elder prevalence was increased by advancing age, female gender and presence of comorbidity and that low serum vitamin D and elevated PTH levels were closely associated with prevalence of frail elder.