A NOVEL C1Q DOMAIN-CONTAINING PROTEIN ISOLATED FROM THE MOLLUSK MODIOLUS KURILENSIS RECOGNIZING GLYCANS ENRICHED WITH ACIDIC GALACTANS AND MANNANS IS VERY PROSPECTIVE FOR BIOMEDICAL PURPOSES

A.V. Grinchenko,A. Kriegsheim,N.A. Shved,A.E. Egorova,D.V. Ilyaskina, T.D. Karp,N.V. Goncharov, I.Yu. Petrova

http://eng.biomos.ru/conference/articles.htmBIOTECHNOLOGY: STATE OF THE ART AND PERSPECTIVES（2021）

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Abstract

A novel C1qDC bivalve protein from the bivalve Modiolus kurilensis (MkC1qDC-1) was identified, isolated and characterized. MkC1qDC-1 demonstrated the inhibition of HeLa cell proliferation and recognition of some cancer cell phenotypes in comparative analysis on several cell lines, suggesting biomedical potential of this protein.

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Key words

glycans,acidic galactans,protein,domain-containing

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