The clinical importance of triglyceride/glucose ratio in the primary prevention of cardiovascular diseases: A retrospective cohort study

Background/Aim: Atherosclerosis plays a significant role in cardiovascular diseases. Dyslipidemia, inflammation, genetics, and environmental factors greatly impact the development and progression of atherosclerosis. This study aimed to investigate the importance of triglyceride-glucose ratio in primary cardiovascular event prevention. Methods: Our retrospective cohort study included 56 patients (39 males, 17 females). Coronary computed tomography angiography (CCTA) images of the individuals were examined, and calcium score was calculated using the Agatston score. Those with a score of zero and those with scores>0 were included in Groups 1 and 2, respectively. Triglyceride/glucose (TyG) ratio and atherosclerotic cardiovascular disease (ASCVD) risk were calculated for all individuals. Results: Among all patients, 69.6% had coronary artery calcium scores (CACs) of greater than zero. The TyG ratios were 0.92 (0.33) and 1.77 (0.83) in Groups 1 and 2, respectively (P