Role of cereal bioactive compounds in the prevention of age-related diseases

In recent years, the potential of antiaging interventions that are effective against age-related diseases is gaining increased scientific interest. In this chapter, contribution of wholegrain-based foods can be considered as part of antiaging dietary interventions that are effective against age-related diseases is discussed. Naturally occurring compounds in wholegrain cereals comprised several categories, namely, nondigestible carbohydrates (fiber), phenolic acids, flavonoids, avenanthramides, lignans, alkylresorcinols, carotenoids, phytosterols, and tocols. This chapter highlights the influence of cereal bioactive compounds in preventing aging disorders and augmenting lifespan based on their influence on oxidative stress, inflammation, cellular senescence, and gut microbiota. Moreover, information presented herein encourages research on wholegrain-based strategies and clinical trials to develop a holistic nutrition-oriented antiaging therapy.