A Rare Case of Kimura Disease in A Black African

Acta Scientific Medical Sciences(2022)

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摘要
Introduction: Kimura disease or eosinophilic lymphogranuloma is a very rare condition.It occurs almost exclusively in patients of Far Eastern origin, but more rarely in Caucasians.It has not been described in black Africans.We report a case. Observation:The patient was 66 years old, a farmer, not known to be a smoker, referred by an ENT specialist for investigation of a swelling of the left parotid region, evolving for 9 years, progressively increasing in volume, painless, accompanied by inflammatory episodes.The clinical examination revealed a patient in good general condition, apyretic, with normo colored conjunctiva.On inspection, there was a swelling of the left parotid region without inflammatory signs of the skin.On palpation, there was a swelling of firm consistency, poorly limited, painless, not flapping, mobile in relation to the superficial and deep planes, measuring approximately 7cm in long axis.Palpation of the contralateral submaxillary region showed a smaller soft mass with a 3 cm long axis.Dermatological examination revealed prurigo.A cervicofacial CT scan showed an enlarged right parotid gland with irregular contours infiltrating the subcutaneous fatty tissue externally, without visualization of lithiasis or bone lysis.The biopsy of the accessory salivary glands revealed a grade 1 chronic sialadenitis.The biological workup was normal except for a major hypereosinophilia of 4400.However, the systematic search for proteinuria was negative.The patient underwent a total right parotidectomy.Anatomopathological study of the specimen concluded to a Kimura disease.Oral corticosteroid therapy was instituted with a good evolution. Conclusion:Kimura's disease is a rare condition, which usually affects Japanese men.It is characterized by subcutaneous nodules predominantly on the head and neck.The prognosis of the disease remains good.
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Kimura Disease
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