The Heart-Work-Calculator: How an Application Could Potentially Simplify the Generation of Noninvasive Left Ventricular Pressure–Volume Loops in Daily Clinical Care

Background: Invasive generated left ventricular pressure-volume loops (PVL) are considered the gold standard in the assessment of left ventricular function and efficiency. In the past, various methods have been established to generate left ventricular PVL noninvasively through echocardiography and simultaneous blood pressure measurement. However, the assessment of noninvasive left ventricular PVL requires complex formulas that hamper its inclusion in daily clinical care. Our aim was to provide a more user friendly option by developing an application which supports the generation of noninvasive left ventricular PVL and its derived left ventricular efficiency parameters.