Nonimaging evaluation of patients with nervous system metastases

Central and peripheral nervous system metastases are common in metastatic cancer. The mainstay of diagnosing this pathology is neuroimaging; however, nonimaging techniques can also be helpful. Electroencephalography, evoked potentials, electromyography, nerve conduction studies, nerve biopsy, and cerebrospinal fluid analysis, including liquid biopsy, are all effective methodologies for diagnosing and assessing treatment response in metastatic disease of the nervous system.