Effects of an intrauterine hyperglycemic environment on fetal brain neurons

Akio Nakamura, Haruka Ookami,Akiyo Toriumi,Hitomi Yoshizaki, Eriko Oogane,Ritsuko Kawaharada

Proceedings for Annual Meeting of The Japanese Pharmacological Society（2022）

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摘要

Introduction: In the neurons of infants born to diabetic mother rats, we found that in utero hyperglycemia promotes excessive advanced glycation endproducts (AGEs). Therefore, our study aimed to elucidate the molecular mechanisms regulating this effect using a neuronal model that mimics the hyperglycemic intrauterine environment.

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关键词

intrauterine hyperglycemic environment,fetal,brain

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