Abstract P293: The Correlations Between NT-proBNP and Cardiac Reserve by Phonocardiogram Exercise Test

Objective: To investigate the correlations between NT-proBNP and Cardiac contractility reserve index(CCRI) and Cardiac reserve index(CRI) and find more theoretical and clinical evidence that CRI, CCRI can reflect the degree of heart failure,promote the use of them in the Primary hospitals and community health service centers. Methods: According to the inclusion and exclusion criteria,155 cases were included in the study, 60 volunteers without cardiovascular disease were selected as the control group, all of them were classed by NYHA functional classification, phonocardiogra were recorded by phonocardiogram exercise test (PCGET) before and after 6 minutes walk test, measured S1 amplitude and heart rate, calculated CCRI, CRI, detected NT-proBNP, and analysed the CCRI, CRI, and NT proBNP correlations. Results: Compared with the healthy group, the NT-proBNP, CCRI, CRI, 6 minutes walking distance were significantly different in different NYHA FC, Moreover, with the increase of NYHA FC level, CRI, CCRI gradually decreased, 6 minutes walk distance gradually shortened, NT-proBNP gradually increased, the differences were statistically significant. Conclusion: The CCRI, CRI and NT- proBNP have good correlations, so they can reflect the classification of cardiac function, they are facilitate, economic, no invasive, rapid, they are worth using widely in primary hospitals and community health service centers.