Mp41-19 phase i nct03738488. feasible 3d printed models of renal cell carcinoma with venous thrombus extension for surgical planning and simulation

You have accessJournal of UrologyCME1 May 2022MP41-19 PHASE I NCT03738488. FEASIBLE 3D PRINTED MODELS OF RENAL CELL CARCINOMA WITH VENOUS THROMBUS EXTENSION FOR SURGICAL PLANNING AND SIMULATION Ines Rivero Belenchon, Carmen Belen Congregado Ruiz, Gorka Gomez Ciriza, Victoria Gomez Dos Santos, Cristina Asensio, Cristina Gonzalez Gordaliza, Ignacio Osman Garcia, Jose Manuel Conde Sanchez, Francisco Javier Burgos Revilla, and Rafael Antonio Medina Lopez Ines Rivero BelenchonInes Rivero Belenchon More articles by this author , Carmen Belen Congregado RuizCarmen Belen Congregado Ruiz More articles by this author , Gorka Gomez CirizaGorka Gomez Ciriza More articles by this author , Victoria Gomez Dos SantosVictoria Gomez Dos Santos More articles by this author , Cristina AsensioCristina Asensio More articles by this author , Cristina Gonzalez GordalizaCristina Gonzalez Gordaliza More articles by this author , Ignacio Osman GarciaIgnacio Osman Garcia More articles by this author , Jose Manuel Conde SanchezJose Manuel Conde Sanchez More articles by this author , Francisco Javier Burgos RevillaFrancisco Javier Burgos Revilla More articles by this author , and Rafael Antonio Medina LopezRafael Antonio Medina Lopez More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002607.19AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Renal Cell Cancer (RCC) accounts for 3-5% of all adults malignancies, and up to 10% are presented with venous thrombus extension (VTE). This worsens prognosis and represents a therapeutic challenge. 3D biomodels are printed copies of patients´ radiological images with visual and tactile components that enhance understanding of anatomy and may improve surgical planning, communication and training. This is a Multicenter Clinical Trial (NCT03738488), which aims to assess the efficacy and efficiency of surgery planning with 3D in RCC with VTE. The objective of the phase I is to obtain a feasible, affordable, accurate and suitable for surgical simulation 3D model. METHODS: A CT image in early arterial and nephrogenic phase was obtained. ITK-snap® and VirSSPA Software® were used for segmentation. The resulting 3D mesh was processed with MeshMixer®. Multiple models were printed using different 3D printers and materials. We evaluated: material, scale, thickness, accuracy, suitability for surgery, cost and printing time. 6 urologists completed a satisfaction questionnaire. RESULTS: 4 models were discarded (Table 1). The selected one was printed with BQ Witbox FDM printer in polyurethane filament with a 0.8 mm thickness and 100% scale. All anatomical structures could be correctly identified with a good accuracy compared to the CT (<5 mm deviation) and the surgery could be performed on it. Model cost was 15€ and whole processing and printing time 48 h. 100% of urologists thought that the obtained 3D model could be useful for surgery planning and simulation. CONCLUSIONS: A feasible and affordable 3D printed model of RCC with VTE was obtained. It was accurate compared to the CT and suitable for surgery simulation. Urologists thought it could be useful for surgery planning and simulation. Source of Funding: Funded by Pfizer © 2022 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 207Issue Supplement 5May 2022Page: e728 Advertisement Copyright & Permissions© 2022 by American Urological Association Education and Research, Inc.MetricsAuthor Information Ines Rivero Belenchon More articles by this author Carmen Belen Congregado Ruiz More articles by this author Gorka Gomez Ciriza More articles by this author Victoria Gomez Dos Santos More articles by this author Cristina Asensio More articles by this author Cristina Gonzalez Gordaliza More articles by this author Ignacio Osman Garcia More articles by this author Jose Manuel Conde Sanchez More articles by this author Francisco Javier Burgos Revilla More articles by this author Rafael Antonio Medina Lopez More articles by this author Expand All Advertisement PDF DownloadLoading ...