Mp21-12 still one out of five men presenting for erectile dysfunction are young than 40 years of age: findings of a real-life cross-sectional study over last decade

You have accessJournal of UrologyCME1 May 2022MP21-12 STILL ONE OUT OF FIVE MEN PRESENTING FOR ERECTILE DYSFUNCTION ARE YOUNG THAN 40 YEARS OF AGE: FINDINGS OF A REAL-LIFE CROSS-SECTIONAL STUDY OVER LAST DECADE Edoardo Pozzi, Paolo Capogrosso, Giuseppe Fallara, Luca Boeri, Christian Corsini, Daniele Cignoli, Massimiliano Raffo, Luigi Candela, Nicolò Schifano, Alessia d'Arma, Rayan Matloob, Federico Dehò, Vincenzo Mirone, Francesco Montorsi, and Andrea Salonia Edoardo PozziEdoardo Pozzi More articles by this author , Paolo CapogrossoPaolo Capogrosso More articles by this author , Giuseppe FallaraGiuseppe Fallara More articles by this author , Luca BoeriLuca Boeri More articles by this author , Christian CorsiniChristian Corsini More articles by this author , Daniele CignoliDaniele Cignoli More articles by this author , Massimiliano RaffoMassimiliano Raffo More articles by this author , Luigi CandelaLuigi Candela More articles by this author , Nicolò SchifanoNicolò Schifano More articles by this author , Alessia d'Arma Alessia d'Arma More articles by this author , Rayan MatloobRayan Matloob More articles by this author , Federico DehòFederico Dehò More articles by this author , Vincenzo MironeVincenzo Mirone More articles by this author , Francesco MontorsiFrancesco Montorsi More articles by this author , and Andrea SaloniaAndrea Salonia More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000002554.12AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Erectile dysfunction (ED) has been demonstrated to be reasonably prevalent among young men (≤40 yr). We aimed to i) assess changes in patterns of reported ED in men ≤40 yr, and ii) compare the sociodemographic and clinical characteristics of ED men ≤40 yr vs. >40 yr of age over a 8-yr period at a single academic centre. METHODS: Data of 1179 patients seeking first medical help for ED and assessed by a single Sexual Medicine expert between 2013 and 2021 were analysed. All patients completed the IIEF at baseline. Descriptive statistics tested the sociodemographic and clinical characteristics of ED men ≤ 40 yr vs. > 40 yr of age. Within the two groups, multivariable linear regression models tested the association between advancing age and IIEF scores. Local polynomial regression models were applied to explore and graphically display ≤ 40 yr patients’ likelihood to report ED over the analysed time frame and to display changes of the IIEF-EF scores over increasing age between the two groups. RESULTS: Overall, median (IQR) age was 52 (41-62) yr. Median (IQR) IIEF-EF was 18 (15-22) at baseline. Of all, 268 (22.7%) were ≤40 yr whereas 911 (77.3%) were >40 yr at baseline. Rates of severe ED according to IIEF-EF did not differ between men ≤40 yr and >40yr (60 (22.4%) vs. 155 (17%)). No significant differences were found for the IIEF domains (-IS, -OS, -SD) but IIEF-OF domains, which scored higher in younger men (9 () vs. 8 (), p=0.002). At baseline, younger patients reported less comorbidities, less active smoking, lower BMI, higher total testosterone (tT) levels than older patients (all p<0.005). At linear regression models, within the ≤ 40 yr group, increasing age was not associated with changes across all IIEF domains. In contrast, in men > 40 yr, increasing age was linearly correlated with decreasing IIE-EF (all p<0.001), after adjusting for tT, BMI, CCI, smoking and arterial hypertension. Figure 1 graphically displays a stable 8-yr temporal trend of ≤40 yr ED patients. CONCLUSIONS: One out of five men seeking first medical help for ED at a single academic centre were younger than 40 yr. This trend has remained stable over the last 8-years. Increasing age among younger patients is not associated with worse erectile function as oppositely occurs among patients > 40 yr. Source of Funding: N/A © 2022 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 207Issue Supplement 5May 2022Page: e331 Advertisement Copyright & Permissions© 2022 by American Urological Association Education and Research, Inc.MetricsAuthor Information Edoardo Pozzi More articles by this author Paolo Capogrosso More articles by this author Giuseppe Fallara More articles by this author Luca Boeri More articles by this author Christian Corsini More articles by this author Daniele Cignoli More articles by this author Massimiliano Raffo More articles by this author Luigi Candela More articles by this author Nicolò Schifano More articles by this author Alessia d'Arma More articles by this author Rayan Matloob More articles by this author Federico Dehò More articles by this author Vincenzo Mirone More articles by this author Francesco Montorsi More articles by this author Andrea Salonia More articles by this author Expand All Advertisement PDF downloadLoading ...