Antioxidant activity of some promising fatty oils: comparative study <i>in vitro</i>

This paper presents the results of the comparative study of the in vitro antioxidant activity of fatty oils obtained by cold-pressing (black cumin, argania prickly, olive oil) which are promising for the use in medical practice. An oil solution of alpha-tocopherol acetate was also used as a comparison. Antioxidant activity was determined by registration of chemiluminescence on the device HLM-003 in systems simulating the production of reactive oxygen species and lipid peroxidation. The study revealed the ability of most samples of the investigated fatty oils to inhibit the generation of reactive oxygen species and lipid peroxidation in model systems in vitro which characterized their antioxidant properties in the comparative aspect with the reference preparation. Samples of black cumin fatty oil showed the greatest antioxidant activity. The optimum fatty oil concentrations for each model system (1 mg/ml and 5 mg/ml) were also selected and the dose-dependent effect on the oil concentration in the system was established.