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Genistein impairs proliferation and induces apoptosis in human leukemia MOLT-4 cells by down-regulation of anti-apoptotic proteins

Firoozeh Abolhasani Zadeh,Mahsa Mardasi,Mohaddeseh Rahbaran,Sadegh Shojaei Baghini,Sahel Rahimi,Parastoo Tambrchi,Ehsan Razeghian

Annals of Cancer Research and Therapy（2022）

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Abstract
Aim: Recently, using natural products has become a rapidly evolving option to treat human malignancies, such as leukemia. Herein, we examined the anti-leukemic effects of flavonoid genistein in human T-cell acute lymphoblastic leukemia (T-ALL) MOLT-4 cell lines.
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