Component composition and antimicrobial activity of the essential oil melilotus offici-nalis (l.) pall, growing in uzbekistan

Nargiza Kudratullaevna Usmanova,Khayrulla Mamadievich Bobakulov, Abdurashid Musakhonovich Karimov,Sobirjan Anarmatovich Sasmakov, Erkin Khozhiakbarovich Botirov, Shakhnoza Sadykovna Asimova, Nasrulla Dzhalilovich Abdullayev

chemistry of plant raw material(2022)

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Abstract
The component composition of the essential oil (EO) from the air-dry and fresh aerial parts of the plant Melilotus officinalis (L.) Pall growing on the territory of the Namangan region of the Republic of Uzbekistan during the flowering period has been studied. The GC-MS method identified 49 compounds in the EO from an air-dry plant, while 22 substances were found in the EO from a fresh plant, which is 98.0% and 99.2% of the total amount of EO, respectively. The main components of EO, both air-dry and fresh aboveground parts, is coumarin, the content of which is 83.2% and 87.9%, respectively. EOs also contained alcohols, carboxylic acids, aldehydes and ketones, a small amount of monoterpenes and oxidized monoterpenes, etc. The antimicrobial activity of essential oil against Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Candida albicans, Pseudomonas aeruginosa, Candida albicans was studied.
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Key words
essential oil,antimicrobial activity,offici-nalis
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