P374. Specific Parameters of Transcranial Near Infrared Light Modulate its Impact on Cerebral Blood Flow

Dan Iosifescu,Katherine Collins,Aura M. Hurtado,Jacek Dmochowski,Luis DeTaboada,Molly K. Irvin,Allison Sparpana,Elizabeth Sullivan,Xiaotong Song,Arwa Adib,Julie A. Clancy,Maia B. Gersten,Kayla M. McEachern,Paolo Cassano

Biological Psychiatry（2022）

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摘要

Transcranial photobiomodulation (t-PBM) with near-infrared light penetrates the cerebral cortex and stimulates mitochondria; it may also have antidepressant effects. In this study we evaluated the dose-dependent effects of t-PBM on cerebral blood flow (CBF) in major depressive disorder (MDD).

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关键词

Major Depressive Disorder, Photobiomodulation, BOLD fMRI

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