麻痹性痴呆临床特征分析

Chinese Journal of Nervous and Mental Diseases(2020)

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Abstract
麻痹性痴呆(general paresis of insane, GPI)是由梅毒螺旋体侵犯脑实质引起,是神经梅毒最严重的一种类型[1].在青霉素时代前,神经梅毒最常见的临床类型为脊髓痨[2],随着抗生素的广泛应用,神经梅毒的临床模式已发生了改变, GPI 已成为神经梅毒患者常见的类型[3-9],但目前多为病案报告,无大样本的前瞻性研究,因此 GPI 的发病率具体几何尚不清楚.
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