Development and validation of a leukocyte-associated immunoglobulin-like receptor-1 prognostic signature for lower-grade gliomas.

Zhansheng Fang,Li Lin,Zewei Tu,Xingen Zhu,Jingying Li, Pengxiang Luo,Kai Huang,Lei Wu

Cancer medicine（2022）

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摘要

These results indicate that LAIR 1 is a latent marker for determining the prognosis of LGG patients. LAIR 1 may also participate a critical part in TIME of LGG by regulating the infiltration of immune cells, suggesting that LAIR 1 might be used as a therapeutic target to regulate the antitumor immune response.

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关键词

immune checkpoints,leukocyte-associated immunoglobulin-like receptor-1,overall survival,tumor immune microenvironment

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