Prophylactic Administration of Cannabidiol Reduces Microglial Inflammatory Response to Kainate-Induced Seizures and Neurogenesis

Neuroscience(2022)

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摘要
•CBD significantly dampens microglial migration and accumulation to the hippocampus.•CBD reduces the number of ectopic neurons deposited in the hippocampal area post seizure.•Although long-term artisanal CBD use does not modify seizure severity, it may depress processes involved in epileptogenesis.
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CBD,DG,KA,NSCs,SE,SGZ,SVZ,WT-NSC
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