Faecal metabolome and its determinants in inflammatory bowel disease.

Arnau Vich Vila,Shixian Hu,Sergio Andreu-Sanchez,Valerie Collij,Bernadien H. Jansen,Hannah E. Augustijn,Laura Bolte,Renate A.A.A Ruigrok,Galeb Abu-Ali,Cosmas Giallourakis, Jessica Schneider,John Parkinson,Amal Al Garawi,Alexandra Zhernakova,Ranko Gacesa,Jingyuan Fu,Rinse K. Weersma

Gut（2023）

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摘要

In this large-scale analysis, we identified alterations in the metabolome of patients with IBD that are independent of commonly overlooked confounders such as diet and surgical history. Considering the influence of the microbiome on faecal metabolites, our results pave the way for future interventions targeting intestinal inflammation.

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关键词

CROHN'S DISEASE,IBD,INTESTINAL MICROBIOLOGY,STOOL MARKERS

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