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Metabolomics profile of 5649 users and nonusers of hormonal intrauterine devices in Finland

Elena Toffol,Oskari Heikinheimo,Pekka Jousilahti,Anna But,Anni Joensuu,Antti Latvala,Timo Partonen,Iris Erlund,Jari Haukka

American Journal of Obstetrics and Gynecology（2022）

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Abstract
The use of hormonal intrauterine devices was associated with several moderate metabolic changes previously associated with reduced arterial cardiometabolic risk. The metabolic effects were independent of duration of use of the hormonal intrauterine devices. Moreover, the metabolic profiles were similar after discontinuation of hormonal intrauterine device use and in never-users.
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Key words
discontinuation of use,duration of use,fertile-aged,hormonal intrauterine devices,metabolic changes,metabolites
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