Selectivity and Maximum Response of Vibegron and Mirabegron for β 3 -Adrenergic Receptors.
Current therapeutic research, clinical and experimental(2022)
摘要
Vibegron showed no measurable β and low β activity compared with mirabegron, which showed low β and some β activity. Both showed considerable selectivity at β-adrenergic receptors; however, vibegron demonstrated near-exclusive β activity and a higher maximum β response.
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关键词
adrenergic receptor,overactive bladder,pharmacology,β-adrenoreceptor
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