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整合素β3在肺腺癌骨转移中的作用及应用价值

MU Jiaqian,TENG Xiaoyan,WEI Lirong,QIU Rong,GUI Pengcheng,DU Yuzhen

China Oncology（2022）

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Abstract
肺癌患者的5年生存率为14％ ～ 17％ [1],转移是肺癌患者死亡的主要原因 [2].肺腺癌是肺癌最常见的病理学类型,骨骼是肺腺癌常见的转移部位 [3],且以溶骨性骨转移多见 [4].肺癌发生骨转移后,易伴有骨痛、神经压迫和高钙血症等骨相关事件,严重影响患者生存质量 [5].
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Key words
|integrin &#x003b2,3|lung adenocarcinoma|bone metastasis|exosomes
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