循环肿瘤细胞PD-L1表达在恶性肿瘤中的研究进展
Cancer Research on Prevention and Treatment（2022）
Abstract
近年来,针对PD-1及PD-L1的研究深入,免疫治疗逐渐兴起,但其在实体肿瘤患者中有效率只有20％左右,如何选择受益人群成为研究者面临的首要问题.最新临床研究表明循环肿瘤细胞(CTC)表面表达的PD-L1能够作为一种潜在的生物标志物,对恶性肿瘤的免疫治疗具有指导作用.本文将对CTC PD-L1在各种实体肿瘤中的表达情况及最新的临床研究进展作一综述.
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Key words
circulating tumor cell,liquid biopsy,prognosis judgment,efficacy evaluation,immunotherapy monitoring
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