索拉非尼新剂型的研究进展及其应用
Fine Chemical Intermediates(2022)
Abstract
索拉非尼抑制肿瘤细胞增殖和肿瘤血管形成,具有双重抗肿瘤靶向作用,但由于口服生物利用度低、耐药性等缺点,临床应用受影响.综述了索拉非尼的新剂型及其应用,以及联合外泌体治疗肝癌的研究进展,为改善临床出现的问题提供思路.
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