Intrinsic phase–amplitude coupling on multiple spatial scales during the loss and recovery of consciousness
Computers in Biology and Medicine(2022)
Abstract
•Spatial-frequency characteristics by phase–amplitude coupling (PAC) for EEG source signals were analyzed.•Theta-alpha and alpha-beta PAC were observed during sevoflurane-induced loss of consciousness (LOC).•PAC was distributed unevenly in specific functional regions during sevoflurane-induced LOC.•Theta-alpha and alpha-beta PAC showed opposite patterns during sevoflurane-induced LOC.•Sevoflurane-induced LOC causes regulated local–global information processing of the brain.
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Key words
Unconsciousness,Anesthesia,Electroencephalogram,Source estimation,Phase–amplitude coupling
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