Bivalirudin or Unfractionated Heparin for Anticoagulation in Pediatric Patients on Continuous Flow Ventricular Assist Device Support: Single-Center Retrospective Cohort Study.

Kriti Puri,Hari P Tunuguntla,Lisa A Hensch,JiaHoi Loh,Shiu-Ki Hui,Asma Razavi,Sebastian C Tume, Timothy J Humlicek,Susan W Denfield,Joseph A Spinner,Swati Choudhry,Jack F Price,William J Dreyer,Iki Adachi,Jun Teruya

Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies（2022）

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摘要

Use of bivalirudin for anticoagulation in patients on CF-VAD support was associated with lesser odds of hemorrhagic complications compared with use of UFH. Bivalirudin "washout" was successful in medical management of six of eight cases of possible pump thrombosis.

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关键词

anticoagulation,direct thrombin inhibitor,pediatric,ventricular assist device

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