Ischemic Preconditioning Improves Handgrip Strength and Functional Capacity in Active Elderly Women

Background: Aging decreases some capacities in older adults, sarcopenia being one of the common processes that occur and that interfered with strength capacity. The present study aimed to verify the acute effect of IPC on isometric handgrip strength and functional capacity in active elderly women. Methods: In a single-blind, placebo-controlled design, 16 active elderly women (68.1 +/- 7.6 years) were randomly performed on three separate occasions a series of tests: (1) alone (control, CON); (2) after IPC (3 cycles of 5-min compression/5-min reperfusion at 15 mmHg above systolic blood pressure, IPC); and (3) after placebo compressions (SHAM). Testing included a handgrip isometric strength test (HIST) and three functional tests (FT): 30 s sit and stand up from a chair (30STS), get up and go time (TUG), and 6 min walk distance test (6MWT). Results: HIST significantly increased in IPC (29.3 +/- 6.9 kgf) compared to CON (27.3 +/- 7.1 kgf; 7.1% difference; p = 0.01), but not in SHAM (27.7 +/- 7.9; 5.5%; p = 0.16). The 30STS increased in IPC (20.1 +/- 4.1 repetitions) compared to SHAM (18.5 +/- 3.5 repetitions; 8.7%; p = 0.01) and CON (18.5 +/- 3.9 repetitions; 8.6%; p = 0.01). TUG was significantly lower in IPC (5.70 +/- 1.35 s) compared to SHAM (6.14 +/- 1.37 s; -7.2%; p = 0.01), but not CON (5.91 +/- 1.45 s; -3.7%; p = 0.24). The 6MWT significantly increased in IPC (611.5 +/- 93.8 m) compared to CON (546.1 +/- 80.5 m; 12%; p = 0.02), but not in SHAM (598.7 +/- 67.6 m; 2.1%; p = 0.85). Conclusions: These data suggest that IPC can promote acute improvements in handgrip strength and functional capacity in active elderly women.