Synthesis and application of the fluorescent furan and imidazole probes for selective in vivo and in vitro cancer cell imaging

Parisa Mehdizadeh Naderi,Kiomars Zargoosh,Mohammad Qandalee,Omidreza Firuzi,Hossein Behmadi,Saman Hossienkhani,Sorous Moasses Ghafary,Carlos J. Durán-Valle

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy（2022）

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摘要

•Fluorescent derivatives were synthesized and applied for cancer cell imaging.•Selective in vivo fluorescent imaging of 4T1 tumors was successfully performed.•Synthesized derivatives showed spectral and chemical stability.•Synthesized derivatives showed large Stokes shift values.

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关键词

Fluorescence imaging,In vitro imaging,In vivo imaging,Furan derivatives,Imidazole derivatives,Cancer cell,Tumor

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