Inflammation During Early Post-Acute Covid-19 is Associated With Reduced Exercise Capacity and Long Covid Symptoms After 1 Year

Matthew S. Durstenfeld,Michael J. Peluso, Punita Kaveti,Christopher Hill,Danny Li, Erica Sander, Shreya Swaminathan, Victor M. Arechiga,Kaiwen Sun,Yifei Ma, Victor Zepeda,Scott Lu,Sarah A. Goldberg,Rebecca Hoh,Ahmed Chenna,Brandon C. Yee,JOhn W. Winslow,christos J. petropoulos,Sithu Win,John D. Kelly, David V. Glidden,Timothy J. Henrich

medRxiv : the preprint server for health sciences（2022）

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摘要

Cardiopulmonary testing to identify etiologies of persistent symptoms in post-acute sequalae of COVID-19 or "Long COVID" should be performed in a manner that allows for assessment of heart rate response to exercise.Therapeutic trials of anti-inflammatory and exercise strategies in PASC are urgently needed and should include assessment of symptoms and objective testing with cardiopulmonary exercise testing.

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