Two new isoflavones from the roots of Sophora tonkinensis
Journal of Asian natural products research(2023)
摘要
Two new isoflavones (1 and 2), as well as eight known ones were isolated from the roots of Sophora tonkinensis Gagnep. Compound 1 represents an unprecedented polymerization pattern constructed by isoflavone and cytisine. Their structures were elucidated by comprehensive spectroscopic data analysis, combined with ECD calculations. Compound 1 displayed significant anti-tobacco mosaic virus (TMV) activity compared with the positive control ningnanmycin. Moreover, compound 6 exhibited potent alpha-glucosidase inhibitory activity with IC50 value of 47.4 mg/L. [GRAPHICS] .
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关键词
Fabaceae,Sophora tonkinensis,isoflavone,anti-TMV,alpha-glucosidase inhibitory activity
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