清瘀方对血管内皮细胞缺血缺氧损伤的保护作用

JOURNAL OF NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE(2009)

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Abstract
目的 观察清瘀方对血管内皮细胞缺血缺氧损伤的影响.方法 应用H_2O_2及Na_2S_2O_4造成的人静脉血管内皮细胞(HUVECs)缺血缺氧模型,通过MTT染色和细胞培养液中乳酸脱氢酶(LDH)的检测,观察清瘀方含药血清对造模细胞的保护作用.结果 较大剂量清瘀方含药血清能明显减少LDH的漏出,抑制H_2O_2及Na_2S_2O_4造成的内皮细胞损伤.结论 清瘀方对缺血缺氧引起血管内皮细胞具有保护作用.
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