Surface-enhanced Raman spectroscopic analysis of centrifugally filtered blood serum samples of hepatitis C patients

Samra Shakeel,Haq Nawaz,Muhammad Irfan Majeed,Nosheen Rashid,Muhammad Rizwan Javed,Ayesha Tariq,Beenish Majeed,Aafia Sehar,Sania Murtaza,Nimra Sadaf,Gull Rimsha,Imran Amin

Photodiagnosis and Photodynamic Therapy（2022）

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摘要

•Surface-enhanced Raman spectroscopy (SERS) technique is employed for the qualitative and quantitative analysis of HCV serum samples.•By using 50 kDa centrifugal filter device the protein containing different molecular weight present in filtrate portions of blood serum samples of hepatitis C virus (HCV) infected patients and healthy ones are separated.•PCA and PLSR techniques has been employed for the qualitative discrimination.

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关键词

Surface-enhanced Raman spectroscopy,Centrifugal filters of 50 kda,Blood serum,Hepatitis C,Principal component analysis,Partial least square regression analysis

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