Acute lymphocytic leukemia in a patient with long-term carbamazepine exposure: Acute lymphoblastic leukemia that develops in a patient who has been using carbamazepine for a long time.

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners(2023)

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摘要
Carbamazepine is an iminostilbene derivative. Carbamazepine is an antiepileptic drug that exhibits a number of side effects such as headache, abdominal pain, high blood pressure, as well as hematological disorders. In addition to causing thrombocytopenia, hypogammaglobulinemia, leukopenia, and neutropenia, it can have serious effects such as agranulocytosis, aplastic anemia, pure red cell aplasia, leukemia, or DRESS syndrome. The incidence of serious side effects from carbamazepine pharmacotherapy is low, and their exact mechanism of action is still unknown.
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关键词
Acute lymphoblastic leukemia,carbamazepine,cytopenia
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