SARS-CoV-2 and Rhinovirus Infections: Are There Differences in Clinical Presentation, Laboratory Abnormalities, and Outcomes in the Pediatric Population?

Maria Fernanda Badue Pereira,Priscila Suguita, Nadia Litvinov, Sylvia Costa Lima Farhat, Camila Sanson Yoshino de Paula, Carolina dos Santos Lazari,Pedro Vale Bede, Juliana Valeria de Souza Framil, Catarina Bueno, Priscila Cristina Abduch Adas Branas, Irina Monteiro da Costa Guimaraes, Marcia Marques Leite, Ana Carolina Barsaglini Navega, Danilo Yamamoto Nanbu, Claudio Schvartsman, Joao Renato Rebello Pinho, Clovis Artur Almeida Silva, Heloisa Helena de Sousa Marques

Revista do Instituto de Medicina Tropical de São Paulo（2022）

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摘要

This study aims to assess COVID-19 and other respiratory viruses in pediatric patients. Between April 17 and September 30, 2020, we collected 1,566 respiratory samples from 1,044 symptomatic patients who were younger than 18 years old to assess SARS-CoV-2 infection. Of these, 919 were analyzed for other respiratory pathogens (ORP). Patients with laboratory-confirmed COVID-19 or ORP were included. We evaluated 76 pediatric COVID-19 infections and 157 other respiratory virus infections. Rhinovirus occurred in 132/157 (84%). COVID-19 patients who were significantly older, had more fevers, headaches and pneumonia than those with ORP. The median white blood cell count was lower in patients with SARS-CoV-2 than in those with ORP (6,470 versus 8,170; p=0.02). COVID-19 patients had significantly worse symptoms than those with ORP.

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Child,COVID-19,SARS-CoV-2,Rhinovirus

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