Low incidence and transient elevation of autoantibodies post mRNA COVID-19 vaccination in inflammatory arthritis.

Rebecca B Blank,Rebecca H Haberman,Kun Qian,Marie Samanovic,Rochelle Castillo,Anthony Jimenez Hernandez, Parvathy Vasudevapillai Girija,Sydney Catron,Zakwan Uddin,Paula Rackoff,Gary Solomon,Natalie Azar,Pamela Rosenthal,Peter Izmirly,Jonathan Samuels,Brian Golden,Soumya Reddy,Mark J Mulligan,Jiyuan Hu,Jose U Scher

Rheumatology (Oxford, England)（2022）

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摘要

In both health and inflammatory arthritis, the risk of autoantibody seroconversion is lower following mRNA-based immunization than following natural SARS-CoV-2 infection. Importantly, seroconversion does not correlate with self-reported IA disease flare risk, further supporting the encouragement of mRNA-based COVID-19 immunization in the IA population.

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关键词

ANA,COVID-19 infection,COVID-19 vaccines,autoantibodies,inflammatory arthritis

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