Diffuse myocardial fibrosis precedes subclinical functional myocardial impairment and provides prognostic information in systemic sclerosis.

Alexander Gotschy,Suzana Jordan,Christian T Stoeck,Constantin von Deuster, Tatiana Peer,Mareike Gastl,Valery Vishnevskiy,Lukas Wissmann,Rucsandra Dobrota,Carina Mihai,Mike O Becker,Britta Maurer,Sebastian Kozerke,Frank Ruschitzka,Oliver Distler,Robert Manka

European heart journal. Cardiovascular Imaging（2023）

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摘要

Subclinical myocardial involvement first manifests as diffuse myocardial fibrosis identified by the expansion of ECV and increased native T1 in VEDOSS patients while subtle functional impairment only occurs in established SSc. Native T1 and GLS have prognostic value for all-cause mortality in SSc patients.

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关键词

cardiovascular magnetic resonance imaging,feature tracking—strain,myocardial tissue characterization,prognosis,systemic sclerosis

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