SCC Antigen Concentrations in Fine-Needle Aspiration Samples to Detect Cervical Lymph Node Metastases: A Prospective Analysis.

Jeroen E van Schaik,Anna C Muller Kobold,Bernard F A M van der Laan,Bert van der Vegt,Bettien M van Hemel,Boudewijn E C Plaat

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery（2023）

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摘要

Measurement of SCC-Ag concentration for detection of SCC lymph node metastases has a sensitivity at least comparable to FNAC and could be used as a relatively cheap screening tool in samples with nondiagnostic or indeterminate FNAC results or when multiple lymph nodes are sampled. However, SCC-Ag in FNA samples has a lower specificity than FNAC assessed by pathologists experienced in head and neck oncology. Addition of CA15-3 measurement did not lead to improved accuracy.

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关键词

SCC-Ag,fine-needle aspiration,lymph node,mucin 1,squamous cell carcinoma,tumor marker

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