A Motif-Based Network Analysis of Regulatory Patterns in Doxorubicin Effects on Treating Breast Cancer, a Systems Biology Study.

Zeinab Dehghan,Seyed Amir Mirmotalebisohi,Marzieh Sameni, Maryam Bazgiri,Hakimeh Zali

Avicenna journal of medical biotechnology（2022）

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摘要

Following our model validation using the existing experimental data, we recommend our other newly predicted biomarkers and pathways as possible molecular mechanisms and side effects underlying the response to Doxorubicin in breast cancer requiring further investigations.

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关键词

Breast cancer,Doxorubicin,Protein-protein interaction network,Regulatory motif,Systems biology

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