High-level correction of the sickle mutation is amplified in vivo during erythroid differentiation
iScience（2022）
摘要
•The gene editing protocol corrects the sickle mutation in ∼30% of engrafting cells•Random assortment of engrafting stem cell clones without clonal dominance was shown•Corrected erythroid cells are preferentially enriched compared with unedited cells
更多查看译文
关键词
genetics,molecular genetics,genetic engineering
AI 理解论文
溯源树
样例
生成溯源树，研究论文发展脉络
Chat Paper
正在生成论文摘要