Parallel chiral sub/supercritical fluid chromatography screening as a framework for accelerated purification of pharmaceutical targets

Journal of Chromatography A(2022)

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摘要
•A parallel multicolumn SFC workflow is introduced to speed up method development.•Automated chiral screening displays a high success rate.•A rapid deployment of enantioseparations for analysis and purification is achieved.•Fast-paced method development via parallel screening with minimized manual intervention.
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关键词
Chiral supercritical fluid chromatography,Parallel column screening,Enantiopurity analysis,Enantiomers purification
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