Effectiveness of autologous haematopoietic stem cell transplantation and conventional immunosuppression in secondary progressive multiple sclerosis: A retrospective propensity-matched case-control study

Autologous haematopoietic stem cell transplantation (AHSCT) suppresses relapses but its effect on disability progression in secondary-progressive multiple sclerosis (SP-MS) seems moderate, and the benefit/risk ratio is still controversial. The effectiveness of AHSCT was therefore evaluated in SP-MS comparing it with conventional immunosuppression with cyclophosphamide (Cy).