NODDI discloses early changes in the normal appearing white matter in paediatric multiple sclerosis

Monica Margoni,Umberto Villani,Silvia Franciotta,Martina Rubin,Margherita Nosadini,Stefano Sartori,Mariagiulia Anglani,Francesco Causin,Paola Perini,Francesca Rinaldi,Alessandra Bertoldo,Paolo Gallo

JOURNAL OF THE NEUROLOGICAL SCIENCES（2021）

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摘要

Paediatric-onset multiple sclerosis (PedMS) is characterized by high degree of brain inflammation and rapid accumulation of white and grey matter damage. Abnormalities in the normal appearing white matter (NAWM) and their clinical relevance in PedMS were investigated by Neurite Orientation Dispersion and Density Imaging (NODDI).

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关键词

multiple sclerosis,white matter

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