Prefrontal activity imbalance and aberrant reconfiguration across functional networks in patients with Parkinson's disease and somatic symptom disorder
JOURNAL OF THE NEUROLOGICAL SCIENCES(2021)
摘要
The altered activity and neurotransmission of the medial prefrontal cortex (mPFC), a key node of the default-mode network, has been associated with the presence of somatic symptom disorder (SSD), a highly prevalent neuropsychiatric disorders in Parkinson's disease (PD). We investigated whether, in SSD patients, the altered activity of the mPFC promotes a functional reconfiguration across brain networks and whether these changes are specific hallmarks of the presence of SSD in PD.
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关键词
prefrontal activity imbalance,parkinson,somatic symptom disorder,functional networks
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