Rheumatoid Factor Recognizes Specific Domains of the IgG Heavy Chain Complexed with HLA Class II Molecules.
ARTHRITIS & RHEUMATOLOGY(2023)
Abstract
The CH1 domain of IgGH binds to the RA-susceptible HLA-DR molecule and is expressed on the cell surface. RF specifically recognizes the CH3 domain of the IgGH/HLA-DR4 complex.
MoreTranslated text
Key words
RA, RF, IgG heavy chain, autoantigens and autoantibodies, major histocompatibility complex
AI Read Science
Must-Reading Tree
Example
![](https://originalfileserver.aminer.cn/sys/aminer/pubs/mrt_preview.jpeg)
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined