Characterization of Typhoid Intestinal Perforation in Africa: Results From the Severe Typhoid Fever Surveillance in Africa Program.

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE(2023)

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Abstract
Low Typhi culture positivity rates, as well as a lack of blood and tissue culture capability in many regions where typhoid remains endemic, significantly underestimate the true burden of typhoid fever. The occurrence of TIP may indicate underlying typhoid burden, particularly in countries with limited culture capability.
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Key words
Salmonella Typhi, intestinal perforation, Africa, typhoid fever, severe typhoid
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