Electrochemical dual-oxidation strategy enables access to α-chlorosulfoxides from sulfides

An electrochemical selective dual-oxidation strategy that enables access to α-chlorosulfoxides from sulphides with the use of aqueous hydrochloric acid as bifunctional reagent has been developed. This strategy features broad substrate scope, high diastereoselectivity and regioselectivity. Importantly, the late-stage modification of amino acids and pharmaceutical derivatives further highlights the utility.