Treatment of Acute Promyelocytic Leukemia in a 94-Year-Old Male Patient: A Case Report

Zongyan Xie,Yunyun Wang, Xi Wang, Min Wang,Wei Qiao

INTERNATIONAL JOURNAL OF GERONTOLOGY(2022)

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摘要
Acute promyelocytic leukemia (APL), more common in young and middle-aged people, is a unique subtype of acute myeloid leukemia. Recently, the experience in the treatment of elderly APL is limited. This report described the first case of APL in a patient older than 90 years in China. With the stealthy onset and no typical symptoms, the diagnosis was made timely based on close detection of laboratory examination. After a comprehensive evaluation of the patient's condition, the patient received half-dose arsenic trioxide (ATO) alone. The patient tolerated this dose well and achieved molecular complete remission. This report also provides clinical experience for the treatment of elderly APL. Copyright (C) 2022, Taiwan Society of Geriatric Emergency & Critical Care Medicine.
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关键词
acute promyelocytic leukemia, elderly, arsenic trioxide, all-trans retinoic acid
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