Association between tumor mutations and meningioma recurrence in Grade I/II disease.
NEUROSURGERY（2022）
Abstract
Mutations in ATM and CREBBP were associated with accelerated meningioma recurrence, and mutations in POLE were protective of recurrence. Each mutation has potential implications for treatment. The effect of these mutations on oncologic outcomes and as potential targets for intervention warrants future study.
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Key words
ATM,CREBBP,POLE,meningioma,molecular genomics
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