VALUE OF USING GABAPENTIN FOR KNEE OA PATIENTS: A COST-EFFECTIVENESS ANALYSIS

Purpose: Pain in individuals with knee OA is understood to be multifactorial. In addition to nociceptive pain arising from tissue pathology, roughly one in three persons with knee OA report nociplastic pain symptoms reflecting peripheral and/or central pain sensitization. This highlights the importance of additional mechanisms that produce pain in persons with OA. Patients with nociplastic mechanisms contributing to their pain may receive less relief from NSAIDs, corticosteroid injections and TKR.