An Update on Secondary Bacterial and Fungal Infections and Their Antimicrobial Resistance Pattern (AMR) in COVID-19 Confirmed Patients.
JOURNAL OF LABORATORY PHYSICIANS(2022)
摘要
Since coronavirus disease 2019 (COVID-19) has limited treatment options, concern has been raised over secondary infections and antimicrobial resistance (AMR) patterns. It has been observed that patients who were infected with COVID-19 were predisposed to develop secondary infections. The purpose of the study is to ascertain the prevalence of the bacterial and fungal coinfections in COVID-19 patients, and also to assess the AMR patterns in the obtained isolates. We have studied 200 clinical samples obtained from 122 COVID-19 positive patients. Pathogens were identified using Vitek 2 system. The demographic and clinical patterns were also observed. A total of 122 patients developed secondary infections. Patients aged more than 40 years were majorly affected ( -value < 0.0001). Respiratory samples ( = 96) were predominant. ( = 68) was the most common pathogen isolated followed by ( = 54) and an overall 6% rise in the Carbapenem resistance was observed in the isolates. To contain the secondary infections in COVID-19 patients, it is imperative to adhere to antimicrobial stewardship program and timely revise the empirical antibiotic policy.
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关键词
antimicrobial resistance,central line associated bloodstream infections,coagulase-negative staphylococcus
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